Preducted Effect-site Concentration of Propofol for I-gel Insertion During Anesthesia Induction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- Concentration of Propofol
研究概览
简要总结
Before anethetic induction, infuse dexmedetomidine 0.5 mcg/kg for 2 minutes and after injection of lidocaine 30 mg, propofol infusion by using target controlled infusion (TCI) pump. Effect site concentraion of propofol start from 5 and changes the concentration as previous response to i-gel insertion as up and down methods
详细描述
Before anethetic induction, infuse dexmedetomidine 0.5 mcg/kg for 2 minutes and after injection of lidocaine 30 mg, propofol infusion by using target controlled infusion (TCI) pump. Effect site concentraion of propofol start from 5 and changes the concentration as previous response to i-gel insertion as up and down methods. Failure of previous subjects are defined as difficulty to mouth open, severe nausea and couph and laryngeal spasm, and not loss of consciousness.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA PS I-II, 20-60 yrs old
排除标准
- •predicted difficulty airway, recent URI, BMI > 30kg/m2, reactive airway disease
研究组 & 干预措施
concentration of propofol in male
after infusion of dexmedetomidine dexmedetomidine 0.5 mcg/kgfor 2 min, infusion of propofol as using target controlled infusion pump. Effect site concentration would be changed as the response to i-gel insertion as up and down method in male
干预措施: propofol concentration (Drug)
concentration of propofol in female
after infusion of dexmedetomidine dexmedetomidine 0.5 mcg/kgfor 2 min, infusion of propofol as using target controlled infusion pump. Effect site concentration would be changed as the response to i-gel insertion as up and down method in female
干预措施: propofol concentration (Drug)
结局指标
主要结局
Concentration of Propofol
时间窗: from i-gel insertion up to 5 min
effect site concentration of propofol
次要结局
未报告次要终点
研究者
Youn Yi Jo
Assistant professor
Gachon University Gil Medical Center