Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study

Phase 1

Completed

• Conditions: Mild Cognitive Impairment
• Interventions: Behavioral: External memory aids training; Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal)

• Registration Number: NCT00609427
• Lead Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Brief Summary

The purpose of this study is to evaluate the effects of training in memory skills vs. use of external memory aids on everyday memory functioning in older people with mild cognitive impairment.

Detailed Description

Some older people experience memory loss that is worse than other people of their age, although they are not demented. This condition is known as mild cognitive impairment (MCI). Healthy older people can learn mnemonic strategies to improve their memory abilities. Can cognitive rehabilitation help people with MCI do better on mental tasks or maintain better functioning in everyday life? This study will evaluate the effects of two different rehabilitation programmes. Patients in the memory training group will learn mental strategies aimed at improving memory. Patients in the memory compensation group will learn to use external memory aids.

Study Timeline

• Study First Submitted: 2008-01-24
• Study First Submitted QC: 2008-02-06
• Study First Posted: 2008-02-07
• Study Start: 2008-05
• Primary Completion: 2010-05
• Study Completion: 2010-05
• Status Verified: 2010-06
• Last Update Submitted: 2010-06-01
• Last Update Posted: 2010-06-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Clinical diagnosis of mild cognitive impairment

Exclusion Criteria

• Unable to speak and understand English
• Unable to comply with treatment program due to significant comorbid illness; OR
• Anticipated inability to attend all study sessions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
EA	External memory aids training	Training in external memory aids
MT	MEMO programme (Inst Universitaire de Geriatrie, Montreal)	Mnemonic training intervention

Primary Outcome Measures

Name	Time	Method
Rey Auditory Verbal Learning Test	19-20 weeks
Wechsler Memory Scale - Logical Memory	19-20 weeks
Face-name associations test	19-20 weeks
Multifactorial Memory Questionnaire - Ability subscale	19-20 weeks

Secondary Outcome Measures

Name	Time	Method
Rivermead Behavioural Memory Test	19-20 weeks
FAS test (non-memory)	19-20 weeks
Category fluency (non-memory test)	19-20 weeks
Victoria Stroop Test (non-memory test)	19-20 weeks
Digit Span (non-memory test)	19-20 weeks
Multifactorial Memory Questionnaire - Strategies and Contentment subscales	19-20 weeks

Trial Locations

Locations (1)

McGill University Health Centre; 🇨🇦 Montreal, Quebec, Canada