Effect of Pursed-Lip Breathing Combined With Number Counting on Blood Pressure and Heart Rate in Hypertensive Urgency Patients: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 112
- 试验地点
- 2
- 主要终点
- Change of systolic blood pressure
研究概览
简要总结
Hypertensive urgency (HT urgency) is an alarm sign of uncontrolled hypertension. It can be aggravated by nonadherent to medication and psychosocial stress. Mindfulness is beneficial for reducing stress, while deep and slow breathing is effective for blood pressure (BP) lowering. The objective of the study was to assess the effect of pursed-lip breathing with number counting (PLB with NC) that promotes mindfulness and a deep/slow breathing pattern on BP and heart rate (HR) in the HT urgency patients.
详细描述
This was a single-blinded randomized controlled trial. Patients aged between 18-80 years old, diagnosed with HT urgency, who presented at the emergency room of Srinagarind hospital (a 1000-bed, tertiary-care level university hospital), Khon Kaen University between September 1st, 2019 to June 30th, 2020, were enrolled. Those with cardiac arrhythmias, acute HF, acute coronary syndromes, acute stroke, acute respiratory failure, alteration of consciousness, and pregnant women were excluded. This study was approved by the Khon Kaen University Ethical Review Board in Human Research (HE611586). All patients gave their written informed consent before the enrollment.HT urgency was defined as SBP >180 mmHg and/or DBP >110 mmHg without any signs or symptoms of target organ damages.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-80 years old patients who diagnosed with HT urgency, who presented at the emergency room
排除标准
- •Patients with cardiac arrhythmias,
- •Acute heart failure
- •Acute coronary syndromes
- •Acute stroke
- •Acute respiratory failure
- •Alteration of consciousness
- •Pregnant women
结局指标
主要结局
Change of systolic blood pressure
时间窗: pre-intervention and 3 hours after the intervention
The change of systolic blood pressure level was assessed.
Change of diastolic blood pressure
时间窗: pre-intervention and 3 hours after the intervention
The change of diastolic blood pressure level was assessed.
Change of heart rate
时间窗: pre-intervention and 3 hours after the intervention
The change of heart rate was assessed.
次要结局
未报告次要终点
研究者
Praew Kotruchin
Assistant professor
Khon Kaen University