Efficacy of prophylactic enteral bromocriptine in reducing the neurogenic fever in severe Traumatic Brain Injury patients in the Trauma Intensive Care Unit - A Randomized placebo Controlled Study - Nil

Institute of medical sciences Banaras hindu university0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年8月19日

试验速览

暂无简介。

•Isolated cases of severe Traumatic brain injury patients with diagnosis of sub arachnoid
•hemorrhage, diffuse axonal injury, frontal contusion, intraventricular hemorrhage admitted in
•the trauma centre within 24 hours of head injury

•1. Bromocriptine hypersensitivity or allergy, Known contraindication to bromocriptine— known ergot
•alkaloid hypersensitivity, known history of syncopal migraine.
•2. Contraindication to oesophageal temperature measurement
•3. Current diagnosis of systemic manifestations like acute and chronic Liver Failure, Renal Failure
•4. Currently being treated with intra or extravascular therapeutic hypothermia – or where therapeutic
•hypothermia treatment is anticipated during the study period
•5. Hyperthermic syndromes: heat stroke, evidence of thyrotoxicosis, malignant hyperthermia,
•Neuroleptic malignant syndrome, or other drug-induced hyperthermia.
•6. Pregnancy or lactating women
•7. Extracorporeal blood circuit therapies: replacement therapy, extracorporeal life support.
•(Ventricular assist device, extracorporeal membrane oxygenation) during the study period.
•8. Patients already taking bromocriptine or dopamine antagonist

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