EUCTR2017-003180-35-GB进行中（未招募）1 期
Feasibility study on the effects of postnatal enalapril on maternal cardiovascular function following preterm pre-eclampsia - PICk-UP
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •- Diagnosis of preterm pre-eclampsia (pPE) in this pregnancy requiring delivery <37 weeks gestation: new or worsening hypertension >20 weeks with proteinuria or other features suggestive of PE (abnormal haematological, biochemical parameters, fetal growth restriction and/or low PlGF)
- •Biochemical / haematological cut-offs:
- •- Platelet count <100 x109/L
- •- Alanine amino transferase > 50units/L
- •- Creatinine >90mmol/L
- •- Abdominal circumference (AC) / estimated fetal weight (EFW) <3rd centile
- •- Or 2 of the following:
- •- AC/EFW <10th centile
- •- AC/EFW crossing centiles by >2 quartiles
- •- Cerebroplacental ratio <5th centile
- •- Umbilical artery PI >95th centile
- •- At time of randomisation:
- •Postpartum, within 3 days of delivery
- •Aged 18 years or over
- •Able to provide informed consent
- •Serum creatinine <100 mmol/l
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 80
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range 0
排除标准
- •Inability to consent
- •Known cardiac disease
- •Contraindication to ACE inhibitors
- •Current ACE inhibitor / ARB use
- •Renal artery stenosis
研究者
相似试验
招募中
3 期
A clinical trial to assess the effect of time-to-time maternal oral health counselling though psychological / oral health interventions on the caries incidence of both pregnant women and their childreCTRI/2022/07/044124Amrita School of Dentistry
已完成
2 期
Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsiaCardiovascular DiseasesPre-Eclampsia Onset Less Than 37 Weeks (Diagnosis)NCT03466333Manchester University NHS Foundation Trust118
尚未招募
不适用
Assessing the after-effect of Prenatal Training Module (PTM) of Newborn Care on Knowledge and Skill of MotherCTRI/2017/12/011013Dr T M A Pai Rotary hospital Karkala
尚未招募
早期 1 期
Comparison of expectant treatment outcomes in pregnant women with preterm premature rupture of membranes (PPROM) at home and hospitalpreterm premature rupture of membranes.Premature rupture of membranesIRCT20181115041666N1Mashhad University of Medical Sciences100
已完成
3 期
Comparison study on the effect of prenatal administation of high dose and low dose folic acid on surem RANKL/OPG ratio in pregnancyEclampsiapregnant women.IRCT2013122315903N1Drug Applied Research Center, Tabriz University of Medical Sciences- Tabriz- iran88