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Clinical Trials/CTRI/2013/06/003741
CTRI/2013/06/003741
Completed
Phase 4

COMPARISION OF EFFECTIVENESS OF DEXMEDETOMIDINE VS ESMOLOL IN BLUNTING OF CARDIOVASCULAR RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION IN TREATED HYPERTENSIVES

nil0 sites90 target enrollmentTBD
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Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Not specified
Sponsor
nil
Enrollment
90
Status
Completed
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
nil

Eligibility Criteria

Inclusion Criteria

  • •Ninety patients of ASA physical status II \& III, of either sex, aged between 35\-65 years and undergoing elective surgery requiring general anaesthesia will be included in the study. Controlled hypertensive patients with blood pressure less than 160/100 mmHg receiving oral antihypertensive medication for a minimum period of six weeks will be studied.

Exclusion Criteria

  • •?Patients with anticipated difficult intubation
  • •?Physical status \> ASAIII
  • •?Hiatus hernia, gastro\-oesophageal reflux disease
  • •?Obesity ( BMI \> 30 kg/m2\)
  • •?Those on long\-term sedatives, hypnotics, antidepressants, drugs affecting nervous system
  • •?Previous myocardial infarction or angina pectoris, congestive heart failure
  • •? Heart blocks
  • •?Neurosurgical patients
  • •?History of allergy to dexmedetomidine or esmolol

Outcomes

Primary Outcomes

Not specified

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