Mobile-based Games for Cognitive Training in Children With Neurodevelopmental Disorders

Not Applicable

Completed

• Conditions: Autism Spectrum Disorder
• Interventions: Behavioral: Game-based cognitive training

• Registration Number: NCT04308915
• Lead Sponsor: Indian Institute of Technology Kanpur

Brief Summary

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with characteristic deficits in social functioning and presence of stereotypic behavior. Several research studies have examined potential deficits in cognitive skills, such as working memory, in this condition. A meta-analysis of the studies aimed at evaluating working memory (WM) in autistic population suggested deficits in visual and verbal aspects of WM. Working memory training has also been studied in other neurodevelopmental disorders such as Attention Deficit Hyperactivity Disorder (ADHD). The study includes development of mobile-based games for training WM and other cognitive skills in patients and the evaluation of such training in reducing symptoms of ASD. These games may also be useful for other neurodevelopmental disorders.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-09-06
• Primary Completion: 2018-10-31
• Study Completion: 2018-10-31
• Status Verified: 2020-03
• Study First Submitted: 2020-03-11
• Study First Submitted QC: 2020-03-12
• Last Update Submitted: 2020-03-13
• Study First Posted: 2020-03-16
• Last Update Posted: 2020-03-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Diagnosis of Autism Spectrum Disorder or another related neurodevelopmental disorder with symptoms of ASD

Exclusion Criteria

• Inability to use smartphones/tablets
• Serious intellectual disabilities.
• Sensory impairment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Game-based training	Game-based cognitive training	Participants play games for cognitive training

Primary Outcome Measures

Name	Time	Method
Corsi Task Total Score	change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)	It is an indicator of working memory. The minimum value is 0, the maximum value has no limit. Higher values mean better outcome.
Corsi Task Block Span	change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)	It is an indicator of working memory. The value ranges between 0 and 9. Higher values mean better outcome.

Secondary Outcome Measures

Name	Time	Method
Autism Treatment Evaluation Checklist Total Score	change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)	Autism Treatment Evaluation Checklist is a measure to evaluate treatments for Autism. The total score ranges between 0 and 179. Higher values mean better outcome.

Trial Locations

Locations (1)

Indian Institute of Technology Kanpur; 🇮🇳 Kanpur, Uttar Pradesh, India