The Impact of Liver Cirrhosis on Outcomes in Trauma Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4,774,035
- 试验地点
- 2
- 主要终点
- Mortality
研究概览
简要总结
Given that there are only a few studies on the effects of cirrhosis on trauma patients and none have addressed the impact cirrhosis has on the incidence of infections, it is important that we study this to determine the mortality in cirrhotic trauma patients and ascertain the incidence of infectious complications in these patients. We hypothesize that trauma patients with cirrhosis will have higher rates of mortality and infectious complications.
详细描述
There have been a select few studies addressing the effects of cirrhosis on trauma patients. These studies show an increase in morbidity and mortality. However, there is limitation in the depth and breadth of analysis. The primary aim of this study is to determine the mortality rates in cirrhotic trauma patients with a secondary end-point being the determination of the incidence of infections associated with these patients.
Given that there are only a few studies on the effects of cirrhosis on trauma patients and none have addressed the impact cirrhosis has on the incidence of infections, it is important that we study this to determine the mortality in cirrhotic trauma patients and ascertain the incidence of infectious complications in these patients. PI hypothesizes that trauma patients with cirrhosis will have higher rates of mortality and infectious complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cirrhotic trauma patients in the United States within 2010-2018
- •Patients ≥ 18 years old
排除标准
- •Patients less than 18 years old
结局指标
主要结局
Mortality
时间窗: 2010-2018
Patient death
Incidence of infectious complications
时间窗: 2010-2018
Incidents of complications with infections
次要结局
- Injury Severity Score(2010-2018)
- discharge date(2010-2018)
- injury characteristics(2010-2018)
- transfusion data(2010-2018)
- hospital and ICU lengths of stay(2010-2018)
- arrival date(2010-2018)
- alcohol use indicator(2010-2018)
- vital signs; pulse rate(2010-2018)
- vital signs; respiration rate(2010-2018)
- Glasgow Coma Scale(2010-2018)
- Patient demographics(2010-2018)
- vital signs; clinical measurements(2010-2018)
- vital signs; temperature(2010-2018)
- drug use indicator(2010-2018)
- ventilator days(2010-2018)
- Abbreviated Injury Scale(2010-2018)
- vital signs; blood pressure(2010-2018)