Effects of high intensity interval training versus endurance exercise on skeletal muscle and circulating biological networks in healthy adults

Professor John Hawley0 sites10 target enrollmentJune 6, 2019

Overview

No summary available.

Registry

who.int

Start Date

June 6, 2019

End Date

November 29, 2019

Last Updated

6 years ago

Study Type

Interventional

Sex

Male

Sponsor

Professor John Hawley

•Males; 18 \- 30 years; BMI 18\.5 \- 24\.9 kg/m2; sedentary and have not performed structured physical activity for 6 months prior to recruitment; no cardiopulmonary abnormalities; no injuries; apparently healthy; ability to pass the ESSA pre\-exercise screening tool and/or obtain general practitioner clearance to exercise; able to ride a stationary cycle ergometer at high intensity

•Known cardiovascular disease or diabetes mellitus; known gastrointestinal disorder; previous bariatric surgery; major or chronic illness that impairs mobility or eating/digestion; known transmissible disease \[e.g. hepatitis, HIV]; known bleeding disorder (i.e. hemophilia A \[factor VIII deficiency], hemophilia B \[factor IX deficiency], von Willebrand disease, or other rare factor deficiencies including I, II, V, VII, X, XI, XII and XIII); taking prescription medications (i.e. beta\-blockers, anti\-arrhythmic drugs, statins, insulin sensitising drugs, or drugs that increase the risk of bleeding \[i.e. anticoagulants, antiplatelets, novel oral anticoagulants \[NOAs], nonsteroidal anti\-inflammatory drugs \[NSAIDs], selective norepinephrine reuptake inhibitors \[SNRI], or selective serotonin reuptake inhibitors \[SSRIs]]); habitual physical activity of greater than or equal to 150 minutes per week of moderate\-intensity exercise; previous bariatric surgery; smokers; current restriction of dietary intake (i.e. actively trying to diet and lose weight); not being weight stable (\+/\- 5 kg) for the last 3 months.