Total Intravenous Anaesthesia: Comparison of Propofol-Ketamine and Propofol-Dexmedetomidine combinations - TIVA

Peoples College of Medical Sciences0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

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•100 adult patients with ASA Gr I-II between age of 18 to 65 years of age willing for participation in study after explanation of study undergoing short surgical procedures will be includd.They will be devided in two groups 1) group will receive Propofol- Ketamine. combination and group 2) will receive Propofol Dexamedetomedine combination. One capsule of Omeprazole 20 mg and one tab of Alprozolam 0.25 mg given at 10.00 PM previous night of procedure.IV fluid Ringer Lactate will be given for fluid resuscitation. Inductio of anesthesia will be done ingroup 1) with Propofol 1.0 mg/Kgbwt and Ketamine 1.0 mg body wt in group 2) with Propofol 1.0 mg/ bodt wt and Dexmedetomedine 1.0 mg body wt. Maintenance with Propofol 2.0 mg and Ketamine 2.0 mg per kg per hour in group 1) and with Propofol 2.0 mg and Dexmedetomedine 0.7 mg per kg per hour in gropup 2). The vital parameters will be observed during operative procedure and postoperative period. The patients will be followed up for any symptoms and signs and vitals recorded in recovery room.

•Patients who didnot give consent for participation. Patients with H/O allergy to any particular drug, allergy to egg or fat, on MAO inhibitors, H/O Liver disorder like jaundice etc. Pregnant woman and patients for long surgeries not included in study.

发起方

Peoples College of Medical Sciences