Regional Anesthesia for the Management of Perioperative Pain for Free Flap Reconstruction of the Head and Neck: A Randomized Prospective Trial
Overview
- Phase
- Phase 4
- Intervention
- Regional Anesthesia
- Conditions
- Pain, Postoperative
- Sponsor
- University of Florida
- Locations
- 1
- Primary Endpoint
- Opioid consumption
- Status
- Withdrawn
- Last Updated
- 6 years ago
Overview
Brief Summary
By utilizing regional anesthesia blocks at the surgery tissue donor sites, it can potentially reduce post-operative pain while also reducing the use of opioids. It can aim to measure the reduction in opioid use, reduction in pain scores, patient satisfaction, and because there is not a current protocol established for regional anesthesia use for free flap reconstruction, and we aim to standardize the procedure.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects undergoing microvascular fibula free flap reconstruction of the head and neck
- •Subjects undergoing primary reconstruction for both benign and malignant etiology
Exclusion Criteria
- •Pregnant women
- •Subjects with true allergies to the study drugs, reporting anaphylaxis in the past
- •Subjects undergoing reconstruction with more than 1 free flap
- •Subjects undergoing secondary reconstructions
- •Subjects undergoing surgery for osteonecrosis
- •History of enrollment in a pain management program
- •Any subject currently enrolled in pain management, or currently taking long acting opioids such as methadone or oxycontin
Arms & Interventions
Fibular free flap-Block performed
For subjects in the experimental/regional anesthesia group for anterolateral thigh or radial forearm free flap, during the procedure a catheter will be placed into the donor site (leg or arm), wound bed
Intervention: Regional Anesthesia
Anterolateral thigh free flap-Block performed
Description: For subjects in the experimental/regional anesthesia group for anterolateral thigh or radial forearm free flap, during the procedure a catheter will be placed into the donor site (leg or arm), wound bed
Intervention: Regional Anesthesia
Radial forearm free flap-Block performed
Description: For subjects in the experimental/regional anesthesia group for anterolateral thigh or radial forearm free flap, during the procedure a catheter will be placed into the donor site (leg or arm), wound bed
Intervention: Regional Anesthesia
Outcomes
Primary Outcomes
Opioid consumption
Time Frame: 72 hours (3 days) post-operatively
Subjects' morphine equivalent dose. Postoperative period commences at extubation.