Combined Anesthesia Considerations in Uro-Genital Robot Assisted Laparoscopic Surgeries: Acute Kidney Injury
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anesthesia; Reaction
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- acute kidney injury
- Last Updated
- 12 years ago
Overview
Brief Summary
The study hypothesis is that regional anesthesia offers better outcome for the patients who underwent robot assisted laparoscopic urogenital surgery.
Detailed Description
The study investigates the effect of combined anesthesia on occurrence of acute kidney injury in robot assisted laparoscopic urogenital surgery.Renal function is assessed according to the new RIFLE and AKIN criteria, and by determining serum and urinary neutrophil gelatinase associated lipocalin.
Investigators
Mihaly Orsolya
MD, PhD
Iuliu Hatieganu University of Medicine and Pharmacy
Eligibility Criteria
Inclusion Criteria
- •signed the informed consent without previous renal function alteration respiratory and hemodynamic stability
Exclusion Criteria
- •refuse to sign the informed consent chronic or and stage renal disease severe systemic diseases
Outcomes
Primary Outcomes
acute kidney injury
Time Frame: 4 days
Acute kidney injury, previously referred as acute renal failure is a serious complication of major surgery. The diagnostic of subclinical alteration of kidney function is possible with the novel biomarkers, such as neutrophil gelatinase associated lipocalin (NGAL). Modified NGAL values can be detected in patients urine and serum at 6 hours from the renal injury. In our study, we assessed the renal function by determining basal creatinine and follow the creatinine values 4 days postoperative. Acute kidney injury (AKI)is defined as a 0.3 mg/ml rise in serum creatinine from baseline, according to the AKIN criteria. NGAL is measured (with ELISA technique) at 6 hours and 12 hours from the induction of the anesthesia. The incidence of AKI will be compared in the different anesthesia techniques for robot assisted urogenital laparoscopic surgery.
Secondary Outcomes
- postoperative outcome(10 days)