Does Pulmonary Rehabilitation Improve Frailty in Chronic Lung Disease?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 65
- 试验地点
- 2
- 主要终点
- Number of Participants With Frailty Phenotype at Baseline and 6 Months
研究概览
简要总结
Frailty is a state of health with predisposition to adverse events, morbidity and mortality. Frailty consists of weakness, slowness, low physical activity, exhaustion, and wasting. Frailty is associated with increased hospitalizations and death in lung disease. It is unknown if pulmonary rehabilitation will improve frailty markers.
详细描述
Individuals referred to pulmonary rehabilitation will be examined for frailty markers. After completing pulmonary rehabilitation, the same tests will be performed. The effects of pulmonary rehabilitation will be examined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Number of Participants With Frailty Phenotype at Baseline and 6 Months
时间窗: Baseline, Six months
Frailty phenotype is 3 or more of: slow gait speed, exhaustion, decreased hand grip strength, decreased activity level, or wasting. Grip strength parameters, gait speed, exhaustion per Fried et al. 2001. Wasting is defined as further decrease in fat free mass by body composition measurement using DEXA. Low physical activity would be activity monitor in lower quartile.
次要结局
- Change in Strength(after completion of pulmonary rehab, approximately 8 weeks)
- Wasting(after pulmonary rehabilation completion, appoximately 8 weeks)
- Change in Gait Speed(pre and post pulmonary rehab, approximately 8 weeks)
- Improvement in Exhaustion(pre and post pulmonary rehab, approximately 8 weeks)
- Change in Physical Activity Level(pre and post pulmonary rehab, approximately 8 weeks)
研究者
Cassie C. Kennedy, M.D.
Consultant for Critical Care Medicine
Mayo Clinic