comparison of the effect of Saffron and Duloxetine on pain and depression in Rheumatoid arthritis

Phase 3

Recruiting

• Conditions: Condition 1: Depression. Condition 2: Depression.; Major depressive disorder, single episode, mild; Major depressive disorder, single episode, moderate

• Registration Number: IRCT20171106037265N1
• Lead Sponsor: Zahedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

ACR criteria for RA
pain intensity at least 40 according to VAS

Exclusion Criteria

current or previous treatment with duloxetin
axis I psychological disorder except MDD
other structural rheumatological disorder except RA
inflammatory , infectious , autoimmune arthritis
active suicidal thoughts

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain in Rheumatoid arthritis. Timepoint: first, third, sixth weeks. Method of measurement: BPI Questionnaire.;Depression in Rheumatoid arthritis. Timepoint: first, third, sixth weeks. Method of measurement: Hamilton Depression Survey Questionnaire.