Comparison of the effect of psychiatric drugs on the improvement of psychological symptoms and disease severity in patients with functional dyspepsia

Phase 4

Recruiting

• Conditions: functional dyspepsia.; Functional dyspepsia

• Registration Number: IRCT20220329054367N2
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

All patients with functional dyspepsia based on ROME-IV
Having a diploma education
Willingness to cooperate in the project
Not having an allergy to Deloxetine and Nortriptyline

Exclusion Criteria

Having any type of serious psychiatric illness (severe anxiety or depression, psychosis, bipolar disorder, anorexia or bulimia nervosa)
Having any other gastrointestinal disease except functional dyspepsia
Taking antidepressants or antipsychotics in the last 6 weeks
Failure to complete the questionnaires
Non-cooperation in follow-ups
causing severe side effects of the drug used (Deloxetine or Nortriptyline)
Pregnancy or breastfeeding during the study period

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anxiety. Timepoint: Measuring anxiety before the start of the study and one, two and three months after the start of the intervention. Method of measurement: Hamilton anxiety questionnaire.;Depression. Timepoint: Measuring depression before the start of the study and one, two and three months after the start of the intervention. Method of measurement: Hamilton depression questionnaire.;Quality of life. Timepoint: Measuring quality of life before the start of the study and one, two and three months after the start of the intervention. Method of measurement: Nippen questionnaire.