Comparing effects of melatonin and duloxetine in the treatment of osteoarthritis
Phase 3
Recruiting
- Conditions
- Osteoarthritis disease.Osteoarthritis of knee
- Registration Number
- IRCT20200516047468N2
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Age over 40 years
Knee osteoarthritis based on ACR creatria for at least 6 months
Feeling pain or discomfort in the knee for at least 3 months on a daily basis or reducing significant limitations on the Joint involved for 1 month according to WOMAC
No history of underlying diseases (including diabetes, inflammatory arthritis)
OCP consumption, smoking
Exclusion Criteria
BMI>30
Recent history of knee surgery
All cases of secondary osteoarthritis
Drug and / or antidepressant use while studying
Major psychiatric diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Knee pain rates based on WOMAC index. Timepoint: Measuring knee pain at the beginning of the study and three months later. Method of measurement: WOMAC index.
- Secondary Outcome Measures
Name Time Method