Novel MRI Techniques in the Evaluation of Pulmonary Vascular Disease
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- pulmonary artery diameter (mm)
研究概览
简要总结
The diagnosis of a patient with pulmonary hypertension (PH) requires many investigations. At present cardiac catheterisation is the cornerstone investigation in these patients where it is used to establish disease severity and estimate prognosis. It is an invasive procedure which is expensive and not without risk to the patient. Despite the multitude of tests performed, identifying those patients with PH who have a poor diagnosis can be difficult. The aim of this study is to improve the assessment of patients with PH using novel magnetic resonance techniques.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All cases referred to the clinic for assessment for possible pulmonary hypertension.
排除标准
- •patients with a cardiac pacemaker or retained temporary pacing wire
- •patients with aneurysm clip
- •non MRI compatible heart valve prosthesis
- •intra orbital metalic foreign body
- •pregnancy
- •metal prosthesis/spinal rods
- •retained shrapnel
- •cochlear implants/bladder stimulator
结局指标
主要结局
pulmonary artery diameter (mm)
时间窗: up to 3 months
Three-dimensional MRI imaging will be used to acquire cardiac dimensions and anatomical ventilation distribution as well as regional partial pressures of oxygen in the lungs.
次要结局
未报告次要终点