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The Effect of Beer, Red Wine and Fruit Juice on Blood Vessel Function in Persons With Cardiovascular Disease

Early Phase 1
Completed
Conditions
Coronary Heart Disease
Registration Number
NCT00382551
Lead Sponsor
Aalborg University Hospital
Brief Summary

To study the effect of red wine, beer and fruit juice on endothelial function in patients with coronary Heart disease.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
49
Inclusion Criteria
  • Men or postmenopausal women with stable coronary heart disease
  • Coronary heart disease should be verified by coronary angiography with at least 50% stenosis in at least one coronary vessel.
Exclusion Criteria
  • Patients with myocardial infarction within the last tree months
  • Persons with a present or earlier alcohol abuse
  • Persons with a present or earlier drug abuse
  • Person with malign disease
  • Persons, that we consider unsuitable to carry through the examines.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Changes in flow-mediated vasodilation after 2 weeks intervention compared with baseline
Secondary Outcome Measures
NameTimeMethod
Lipid status after 2 weeks intervention compared with baseline
Effects in Coagulation factors after 2 weeks intervention
Effects on markers of inflammation after 2 weeks intervention
Effects on markers of endothelial function after 2 weeks intervention
Changes in the overall antioxidant activity in plasma after 2 weeks intervention

Trial Locations

Locations (1)

Department of Cardiology, Aalborg Hospital, Science and Innovation Center

🇩🇰

Aalborg, Denmark

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