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Clinical Trials/NCT04204590
NCT04204590
Completed
Not Applicable

Feasibility Study of a Systematic Approach for Deprescribing of Statins and Proton Pump Inhibitors in Nursing Home Residents

Zuyderland Medisch Centrum1 site in 1 country75 target enrollmentApril 2, 2018
ConditionsPolypharmacy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Polypharmacy
Sponsor
Zuyderland Medisch Centrum
Enrollment
75
Locations
1
Primary Endpoint
Decrease in pill burden (the dose of statins and PPI's)
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Deprescribing, the process of safely reducing or discontinuing unnecessary or harmful medication, has the potential to decrease polypharmacy and improve health outcomes. In this study a structured implicit algorithm, focusing on both extrinsic medication factors (eg change in disease) and intrinsic patient factors (eg. pill burden) will be used.

Registry
clinicaltrials.gov
Start Date
April 2, 2018
End Date
July 3, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Zuyderland Medisch Centrum
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Participant uses a statin and/or a proton pump inhibitor.
  • Participant signs informed consent.
  • Participant is a nursing home resident.

Exclusion Criteria

  • Participant is there for short term nursing home admission (\<3 months)
  • Participant is there for hospice admission.

Outcomes

Primary Outcomes

Decrease in pill burden (the dose of statins and PPI's)

Time Frame: 3 and 6 months after intervention.

On T0 (intervention) and on T1 + T2 (3 and 6 months after intervention), we will measure the dose of PPI's and statins on the medication list of every participant. These are provided by the pharmacist.

Decrease in pill burden (the number of statins and PPI's)

Time Frame: 3 and 6 months after intervention.

On T0 (intervention) and on T1 + T2 (3 and 6 months after intervention), we will measure the number of PPI's and statins on the medication list of every participant. These are provided by the pharmacist.

Secondary Outcomes

  • Feasibility to use this algorithm.(3 and 6 months after intervention)
  • All possible negative side effects of deprescribing (e.g. nausea, symptom recurrence)(From intervention to six months after intervention)

Study Sites (1)

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