A comparison of two stem cells utilization methods; intravenous and intra alveolar injection by bronchoscope on outcome of severe lung contusio
- Conditions
- lung contusion.Contusion of lungS27.32
- Registration Number
- IRCT20101220005426N12
- Lead Sponsor
- Kerman University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
The pressure of arterial oxygen to inspiratory oxygen should be less than 180(PaO2/FIO2<180)
Bilateral infiltration with pulmonary edema in anterior lung radiography
Pulmonary contusion greater than 40% in chest CT scan
The need to transfer to the intensive care unit due to respiratory failure
Criteria 1-4 must all be present within a 24-hour period at the time of study entry
More than 96 hours have passed since the patient's ARDS trauma
Pregnant or lactating woman
Presence of any active malignancy (other than nonmelanoma skin cancer) that requires treatment within 2 years
Any irreversible disease such as malignancies and a condition with a 50% chance of death within the next six months
Moderate to severe liver disorder based on Child-Puff criteria<12
chronic obstructive pulmonary disease(COPD)
The patient has undergone a lung transplant
The patient's lack of consent, or if the patient is unable to answer, the patient's guardian's lack of consent
A patient who is not expected to be alive in the next 24 hours according to the Apache criteria
Class III or IV pulmonary hypertension
Pulmonary embolism or deep vein thrombosis in the past three months
Brain trauma
Transfusion of large volume of blood (injection of more than 10 units of blood in the last 24 hours)
The presence of heart failure, kidney and diabetes
Patients in a state of shock and previous concurrent contusion
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method