Impact of intra and postoperative oral erythromycin on gastric tube motility in patients undergoing esophageal resection.
Phase 2
Completed
- Conditions
- Health Condition 1: null- Delayed gastric emptying after esophagectomy
- Registration Number
- CTRI/2012/11/003152
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 59
Inclusion Criteria
1.Proven histological diagnosis of esophageal cancer
2.ECOG performance status 0,1
3.Cardiopulmonary reserve adequate for esophageal surgery
4.American Society of Anaesthesiologists (ASA) grade I or II
5.Treatment plan of total esophageal resection
6.Esophageal substitution by stomach tube
7.Posterior mediastinal route of reconstruction
8.Patient available for follow up
Exclusion Criteria
1.Patients with a known allergy to erythromycin or other macrolides
2.Pyloric drainage procedure performed
3.Colonic reconstruction
4.Pregnant women
5.Patients on prokinetic drugs, astemizole, terfenadine and pimozide
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method