IRCT138803031187N2
Completed
Phase 3
Comparing therapeutic effects of sodium bicarbonate with magnesium sulfate in moderate and severe acute organophosphorous pesticide poisoning.
Vice Chancellor for Research, Mashhad University of Medical Sciences (MUMS)0 sites120 target enrollmentTBD
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Moderate and severe acute Organophosphorous pesticide poisoning.
- Sponsor
- Vice Chancellor for Research, Mashhad University of Medical Sciences (MUMS)
- Enrollment
- 120
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients aged 14 to 65 years old with moderate and severe acute organophosphorous pesticide poisoning referring to Imam Reza Hospital, Mashhad, Iran who or whose guardian has confirmed the relevant informed consent.
- •Exclusion criteria: Any evidence of conductive heart diseases and myocardial injuries (inspected by Electrocardiography and plasma Troponin, every 12 hours respectively); renal dysfunction (less than 100 ML urine output for every 4 hours); concurrent administration of Digitals or Central Nervous System suppressors or Neuromuscular Junction blockers (through patients' drug history); any manifestation of magnesium intoxication (through physical examination every 2 hours while administrating magnesium sulfate).
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 2
Therapeutic effects of intravenous lipid emulsion in tricyclic antidepressants toxicityTricyclic antidepressants toxicity.Poisoning by psychotropic drugs, not elsewhere classified/Tricyclic and tetracyclic antidepressantsIRCT2012061610017N2Tehran University of Medical Sciences108
Recruiting
Phase 2
Evaluation of the effect of oral sodium bicarbonate on the symptoms of overactive bladder and acidic urineover active bladder.Overactive bladderN32.81IRCT20131203015634N3Shahid Beheshti University of Medical Sciences36
Recruiting
Phase 3
The effect of mouthwash on the treatment of oral mucositiscancer.Carcinoma in situ of other and unspecified digestive organsIRCT20190703044082N3Hamedan University of Medical Sciences144
Recruiting
Phase 3
Comparison effect of intravenous sodium bicarbonate and sodium chloride combination versus intravenous sodium chloride hydration in reducing of amphotericin B-induced nephrotoxicityIRCT20161010030246N4Shiraz University of Medical Sciences40
Not yet recruiting
Phase 3
Evaluation of Additive effect of sodium bicarbonate with early goal-directed therapy in management of patients with severe sepsis and septic shockCondition 1: Severe sepsis and septic shock. Condition 2: Metabolic acidosis.Other shockAcidosisR57.8E87.2IRCT20220310054246N1Mashhad University of Medical Sciences36