IRCT20161010030246N4RecruitingPhase 3
Comparison effect of intravenous sodium bicarbonate and sodium chloride combination versus intravenous sodium chloride hydration in reducing of amphotericin B-induced nephrotoxicity
Trial Snapshot
- Phase
- Phase 3
- Status
- Recruiting
- Enrollment
- 40
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 15 years to no limit (—)
- Sex
- All
Inclusion Criteria
- •Age over 15 years
- •Receive amphotericin for at least 7 days
- •No history of kidney disease (including chronic kidney disease) and hemodialysis
- •Signing up the informed consent form
Exclusion Criteria
- •Heart failure class 3 and 4
- •Known liver failure
- •Known acute or chronic kidney disease
- •Alkalosis (pH greater than 7.5 or sodium bicarbonate plasma greater than 30 meq / lit)
- •Symptomatic hypocalcemia, hypokalemia or hypomagnesemia
- •Sensitivity and any adverse effect that occurred after the injection of bicarbonate in the patient.
Investigators
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