The effects of different types and intensities of exercise on arterial stiffness and blood pressure throughout pregnancy.

Not Applicable

Completed

• Conditions: pregnancy; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation; Reproductive Health and Childbirth - Normal pregnancy

• Registration Number: ACTRN12622000982718
• Lead Sponsor: Courtney Giles

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-13
• Study Completion: 2023-04-24
• Last Update Posted: 26 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 22

Inclusion Criteria

Pregnant women less than 30 weeks gestation, willing to visit the exercise clinic 3 times per week for exercise sessions.

Exclusion Criteria

Diagnosed gestational health conditions that are considered absolute contraindications to exercise:
Ruptured membranes, premature labour
Persistent second or third trimester bleeding/placenta previa
Pregnancy-induced hypertension or pre-eclampsia
Incompetent cervix
Evidence of intrauterine growth restriction
High-order pregnancy (e.g., triplets)
Uncontrolled Type I diabetes, hypertension or thyroid disease, other serious cardiovascular, respiratory or systemic disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in arterial stiffness as measured by pulse wave velocity using a SphygmoCor system[ Measured at 3 timepoints in each session:<br>Following 5 minutes of supine rest pre exercise. <br>Immediately following exercise.<br>5-10 minutes post exercise. ];Change in blood pressure measured with sphygmomanometer & stethoscope (manual reading)[ Measured at 3 timepoints in each session:<br>Following 5 minutes of supine rest pre exercise. <br>Immediately following exercise.<br>5-10 minutes post exercise. ];Mean Arterial Pressure calculated from SBP and DBP (formula > MAP = (SBP + (2DBP))/3)[ Measured at 3 timepoints in each session:<br>Following 5 minutes of supine rest pre exercise. <br>Immediately following exercise.<br>5-10 minutes post exercise. ]

Secondary Outcome Measures

Name	Time	Method
Augmentation index measured as pulse wave analysis using a SphygmoCor system[ Measured at 3 timepoints in each session:<br>Following 5 minutes of supine rest pre exercise. <br>Immediately following exercise.<br>5-10 minutes post exercise. ];Heart rate measured using HR monitor chest strap[ Measured constantly throughout each session];Foetal heart rate measured with Foetal Doppler[ Measured at 3 timepoints in each session:<br>Following 5 minutes of supine rest pre exercise. <br>Immediately following exercise.<br>5-10 minutes post exercise. ];Rating of perceived exertion (RPE) reported by the participant on the Borg Scale (6-20)[ Measured during each session.<br>Session 1 & 2: every 5 minutes of exercise<br>Session 3: every minute of exercise];Central blood pressure measured using a SphygmoCor system[ Measured at 3 timepoints in each session:<br>Following 5 minutes of supine rest pre exercise. <br>Immediately following exercise.<br>5-10 minutes post exercise. ]