Norepinephrine Weaning in Septic Patients
Phase 4
Completed
- Conditions
- Septic Shock
- Registration Number
- NCT00763906
- Lead Sponsor
- Association pour le Développement de la Recherche et de l'Enseignement en Médecine d'Urgence
- Brief Summary
The weaning rate of vasopressors drugs is usually chosen empirically by the clinician in critically patients. The investigators applied fuzzy logic principles to modify intravenous norepinephrine infusion rates during norepinephrine infusion in septic patients in order to reduce the duration of shock. The investigators goal was to reduce the duration of poorly controlled hemodynamic status.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Septic shock
Exclusion Criteria
- Less than 18 years
- Pregnancy
- Weight above 135 kg
- Requirement for continuous epinephrine infusion
- Severe head injury, stroke, a comatose state following cardiac arrest
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Time to shock resolution defined as cessation of vasopressor support
- Secondary Outcome Measures
Name Time Method 28 days survival, total amount of norepinephrine infused, duration of mechanical ventilation, and length of stay in the ICU
Trial Locations
- Locations (1)
Réanimation
🇫🇷Bobigny, Seine-Saint-Denis, France
Réanimation🇫🇷Bobigny, Seine-Saint-Denis, France