Comparison of the effect of anesthesia with sevoflurane versus isoflurane on blood glucose trends in intracranial mass excision surgery
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To note the baseline blood glucose level (before induction) and then the hourly change in intraoperative glucose levels with the use of sevoflurane or isoflurane as a maintenance inhalational agent.
研究概览
简要总结
This study is a prospective double blind randomizedclinical trial. Aim of the study is to compare the c in non diabetic patientsundergoing intracranial mass excision surgery. The objective of the study is tosee the change in hourly blood sugar level trends from baseline, with the intraoperativeuse of inhalational agents; sevoflurane and isoflurane for maintainence.This study is a prospective double blind randomizedclinical trial. Aim of the study is to compare the c in non diabetic patientsundergoing intracranial mass excision surgery. The objective of the study is tosee the change in hourly blood sugar level trends from baseline, with the intraoperativeuse of inhalational agents; sevoflurane and isoflurane for maintainence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of any sex, non diabetic, ASA status I & II and posted for intracranial mass excision surgery under general anesthesia.
排除标准
- •The patients who are diabetic, have disorders of glucose metabolism, are pregnant and lactating , have renal, cardiovascular, pulmonary or hepatic disease, are chronic alcoholic, are taking insulin, oral hypoglycemic agents, antipsychotic drugs and beta adrenergic blocking drugs or are not willing to give consent.
结局指标
主要结局
To note the baseline blood glucose level (before induction) and then the hourly change in intraoperative glucose levels with the use of sevoflurane or isoflurane as a maintenance inhalational agent.
时间窗: Before induction and every hour after induction till completion of surgery
次要结局
- To note the baseline heart rate, saturation and mean arterial blood pressure and intraoperatively every 2 hour after induction.(Before induction and every two hour after induction till completion of surgery)