Smoking Cessation Intervention in Acute Orthopedic Surgery - A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 105
- 主要终点
- Postoperative complications including wound related complications
研究概览
简要总结
The purpose of this study was to evaluate if an intervention with smoking cessation starting during the acute hospitalization period and continuing during the acute postoperative phase of 6 weeks would reduce the frequency of overall postoperative complications and wound infections in patients with acute musculoskeletal injuries requiring surgical treatment. The secondary aims were to study the short and the long term (1 year) abstinence rate, functional outcome, health related quality of life as well as costs.
详细描述
Tobacco smoking is a major health problem. The effect of a smoking cessation intervention prior to elective orthopedic surgery has been evaluated previously. However, as far as we know there are no prospective randomized studies investigating the effect of smoking cessation on complication rate in patients with acute musculoskeletal injuries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •daily smoker: more than 2 cigarettes per day for at least one year
- •acute fracture of an extremity, in need of surgical treatment
- •oral and written consent
排除标准
- •pregnancy
- •alcohol or drug abuse prohibiting compliance with the study protocol
- •living outside the county of Stockholm prohibiting follow-up
- •a severe mental illness including dementia
- •inability to read and understand Swedish
结局指标
主要结局
Postoperative complications including wound related complications
时间窗: 6-12 weeks
次要结局
- Abstinence rate and functional outcome including HRQoL(1 year)