The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups

Not Applicable

Completed

• Conditions: Periodontal Inflammation
• Interventions: Other: diode laser; Other: non surgical scaling

• Registration Number: NCT06140394
• Lead Sponsor: Faculty of Dental Medicine for Girls

Brief Summary

the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients

Detailed Description

2 ml of unstimulated saliva will be collected using spitting method, the collected samples will then be analyzed using Elisa technique for salivary Inducible nitrous oxide synthase levels.

Study Timeline

• Study Start: 2023-04-29
• Study First Submitted: 2023-11-12
• Study First Submitted QC: 2023-11-16
• Study First Posted: 2023-11-20
• Status Verified: 2024-06
• Primary Completion: 2024-06-25
• Study Completion: 2024-06-25
• Last Update Submitted: 2024-06-27
• Last Update Posted: 2024-06-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• males and females
• aged below 40 or above 60
• periodontitis stage 2
• no tooth loss due to periodontitis

Exclusion Criteria

• smoking habits
• history of antibiotics
• history of systemic diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
old age group	non surgical scaling	old age group above 60 years old
young aged group	non surgical scaling	young age group below 40 years old
old age group	diode laser	old age group above 60 years old
young aged group	diode laser	young age group below 40 years old

Primary Outcome Measures

Name	Time	Method
clinical parameters (gingival index)	6 months	measurement if the gingival index using scoring system. A score from 0.1-1.0 = mild inflammation; 1.1-2.0 = moderate inflammation from, and 2.1-3.0 signifies severe inflammation.
clinical parameters (clinical attachment loss)	6 months	measurement of clinical parameters clinical attachment loss in millimeters

Secondary Outcome Measures

Name	Time	Method
assessment of inducible nitrous oxide synthase levels	3 months	measurement of inducible nitrous oxide synthase levels in different age groups before the procedure and after using Elisa kit.

Trial Locations

Locations (2)

Hamdy Nassar; 🇪🇬 Cairo, Egypt

Al-Azhar University; 🇪🇬 Cairo, Nasrcity Nasr Street, Egypt