MedPath

One Week Aligner Evaluation

Completed
Conditions
Malocclusion
Registration Number
NCT02603289
Lead Sponsor
Align Technology, Inc.
Brief Summary

The purpose of this study is to demonstrate that changing aligners weekly provides similar results to changing aligners every two weeks.

Detailed Description

The Invisalign® System consists of a series of clear plastic aligners that are intended to replace conventional wire and bracket technology for many orthodontic cases. Each custom manufactured aligner exerts gentle, continuous forces to move teeth incrementally from their original state to a final, treated state. The aligners are designed to optimally move each tooth at a speed that follows physiologic principles. The purpose of this study is to demonstrate that changing aligners weekly provides similar results to changing aligners every two weeks.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
287
Inclusion Criteria
  • Subject must have fully erupted dentition except for 2nd and 3rd molars
  • For Teen treatment group, subjects ages <17 years of age
  • For Adult treatment group, subjects ≥17 years of age
Exclusion Criteria
  • Subject has undergone any accelerated orthodontic treatment prior to or during treatment as part of this study
  • Subject with active caries
  • Subject with periodontal disease
  • Subject with TMD symptoms
  • Subject has known allergy to latex or plastic
  • Subjects who are pregnant or will become pregnant during treatment

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Planned to Final Tooth PositionThrough study completion, an average of 2 years

Test vs Historical Control Group

Secondary Outcome Measures
NameTimeMethod
Treatment timeThrough study completion, an average of 2 years

Length of treatment

Subject Quality of LifeThrough study completion, an average of 2 years

Assessment of QoL

Trial Locations

Locations (24)

Dr. Thomas Marcel

🇺🇸

Livermore, California, United States

Dr. Mary Cooke

🇺🇸

Napa, California, United States

Dr. Bella Shen Garnett

🇺🇸

San Francisco, California, United States

Align Technology, Inc.

🇺🇸

San Jose, California, United States

Dr. Robery Van den Berg

🇺🇸

San Ramon, California, United States

Dr. Anil Idiculla

🇺🇸

Lone Tree, Colorado, United States

Dr. Ryan Caudill

🇺🇸

Merritt Island, Florida, United States

Dr. Sean Holliday

🇺🇸

Pearl City, Hawaii, United States

Dr. Jeff Mastroianni

🇺🇸

Glen Carbon, Illinois, United States

Dr. Mark Perelmuter

🇺🇸

Louisville, Kentucky, United States

Scroll for more (14 remaining)
Dr. Thomas Marcel
🇺🇸Livermore, California, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.