The Study of Ropivacaine Median Effective Concentration in Ultrasound-guided Supraclavicular Brachial Plexus Block
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- the affection of nerve block
研究概览
简要总结
To determine the median effective concentration of ropivacaine hydrochloride for ultrasound-guided supraclavicular brachial plexus block. The result can provide reference for choosing appropriate drug concentration in clinical anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA I or II
排除标准
- •upper limb paresthesia
- •allergic to local anesthetics
- •surgery history of clavicle
- •BMI>30kg/m^2
研究组 & 干预措施
ropivacine
干预措施: ropivacaine (Drug)
结局指标
主要结局
the affection of nerve block
时间窗: 30 minutes
The anesthetic efficacy of five nerves, respectively named lateral antebrachial cutaneous nerve, medial cutaneous nerve of the forearm, radial nerve, median nerve, and ulnar nerve was assessed within 30 min after anesthesia. The next concentration of ropivacaine was adjusted according to the response of the previous patient using up-down sequential allocation.
次要结局
未报告次要终点
研究者
Yu Shan
The study of ropivacaine median effective concentration in ultrasound-guided supraclavicular brachial plexus block
Shanghai Jiao Tong University Affiliated Sixth People's Hospital