Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural Effusion

Phase 4

Completed

• Conditions: Malignant Pleural Effusions (Mpe)- Pleurodesis; Pleurodesis

• Registration Number: NCT06744946
• Lead Sponsor: Mohamed Sabry

Brief Summary

Comparing Two Methods to Treat Fluid Build-up in Chest for Cancer Patients:Talc Powder Surgery versus Chest Tube Medicine.

Detailed Description

Closure of the space where the effusion is recurrently accumulated through talc poudrage in thoracoscopy or bleomycin - tranxemic acid solution injection in chest tube.

Study Timeline

• Study Start: 2024-09-01
• Primary Completion: 2024-10-29
• Status Verified: 2024-12
• Study Completion: 2024-12-04
• Study First Submitted: 2024-12-07
• Study First Submitted QC: 2024-12-19
• Last Update Submitted: 2024-12-19
• Study First Posted: 2024-12-20
• Last Update Posted: 2024-12-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1. Adult patients (more than 18 years) with malignant pleural effusion or highly suspected exudate.

2. Fit patients for the procedure selected.

Exclusion Criteria

1. Inability to provide informed consent for the procedure.
2. Hemodynamically unstable patients.
3. Bleeding diathesis.
4. Uncontrolled cough.
5. Hypoxic index less than 300.
6. Endobronchial obstruction.
7. Pleural thickening with trapped lung.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Dyspnea Borg Scale	one month	the rate of shortness of breath from number 0 to number 10

Trial Locations

Locations (1)

Chest Department -Faculty of Medicine; 🇪🇬 Alexandria, Azarita, Egypt