Study of factors limiting physical exercise and effect of resources associated with rehabilitation in chronic cardiorrespiratory diseases
- Conditions
- VentilationExerciseC08.381.495.389C14.280.434
- Registration Number
- RBR-5ygrvmc
- Lead Sponsor
- niversidade Federal de São Carlos
- Brief Summary
IV applied during high-intensity exercise unloads the respiratory musculature, enhancing oxygen supply to the peripheral musculature, providing longer exercise time and reducing fatigue symptoms in patients diagnosed with COPD and HF.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
50 years or more; diagnosis of coexisting COPD and HF; FEV1 to CVF ratio of 0.7; left ventricular ejection fraction less than 50%; New York Heart Association Functional Classification I-IV; optimized medical therapy
musculoskeletal disorders or neurological conditions that affect exercise capacity; deterioration of the clinical condition requiring hospitalization 3 months before the study; diagnosis of malignant disease; implantable pacemaker; myocardial infarction 3 months before the study; complex cardiac arrhythmias
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the acute effects of the bilevel during constant load exercise on ventilatory, cardiocirculatory mechanical responses, muscle and brain oxygenation, endothelial function and exercise tolerance in patients with COPD-IC.
- Secondary Outcome Measures
Name Time Method It is hoped that the bilevel can improve exercise intolerance in the face of COPD-IC, reduce ventilatory and circulatory mechanical changes, and also improve endothelial function and central and peripheral oxygen supply in these patients.