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Clinical Trials/NCT03609255
NCT03609255
Completed
Not Applicable

Health Effects of Reducing Sedentary Behavior

Texas Tech University1 site in 1 country21 target enrollmentAugust 13, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
General Population
Sponsor
Texas Tech University
Enrollment
21
Locations
1
Primary Endpoint
Stress improvement in stress management group (SR)
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

A recent review indicated that sedentary behavior has been associated with increased morbidity and mortality but the intervention studies frequently focus only on changing sedentary behavior (reducing sedentary time) without measuring health-associated outcomes. Elevated cortisol (related to stress) has been linked with health risks. Improved physical fitness has been linked with improved cortisol responses to psychosocial stressors. In addition, increased physical activity induced favorable effects upon low density lipoprotein, high density lipoprotein, and total cholesterol. Previous study also indicated that increasing daily steps have positive effect on blood glucose in people with impaired glucose tolerance. Ultimately, the investigators think that sedentary intervention and stress management may have benefits on these health indicators. As such the investigators will examine whether sedentary intervention or stress management can have positive effect on human health by measuring salivary cortisol, blood lipid profile, fasting blood glucose, blood pressure, resting energy expenditure, and body composition.

Registry
clinicaltrials.gov
Start Date
August 13, 2018
End Date
October 8, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Martin Binks

Associate Professor

Texas Tech University

Eligibility Criteria

Inclusion Criteria

  • Age: 18-65 years.

Exclusion Criteria

  • Unable/unwilling to provide informed consent.
  • Having mobility impairment.
  • Current severe untreated depression (i.e., score in the severe depression range on the Hospital Anxiety and Depression Scale; HADS).
  • Women who are pregnant or nursing.
  • Currently smoking (within last 12 months).
  • Currently use medications that affect salivary cortisol level (i.e. prednisone, dexamethasone).
  • Have been diagnosed Addison's disease.

Outcomes

Primary Outcomes

Stress improvement in stress management group (SR)

Time Frame: Baseline (pre-intervention) and 4 weeks (post-intervention)

Improvement in stress as measured via salivary cortisol in SR.

Compare the changes of stress levels between SB and SR

Time Frame: Baseline (pre-intervention) and 4 weeks (post-intervention)

Compare the changes of stress levels as measured via salivary cortisol between SB and SR.

Stress improvement in sedentary behavior group (SB)

Time Frame: Baseline (pre-intervention) and 4 weeks (post-intervention)

Improvement in stress as measured via salivary cortisol in SB.

Daily steps

Time Frame: Baseline (pre-intervention) and 4 weeks (post-intervention)

Changes in daily steps measured via pedometer.

Secondary Outcomes

  • Changes in high density lipoprotein (HDL) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in low density lipoprotein (LDL) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in blood pressure in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in TG between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in body fat in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in fasting blood glucose in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in TC between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in triglyceride (TG) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in weight in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in high density lipoprotein (HDL) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in LDL between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in fasting blood glucose between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in blood pressure between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Change in resting energy expenditure in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in body fat in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in total cholesterol (TC) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in blood pressure in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in triglyceride (TG) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in fasting blood glucose in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in weight between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Change in resting energy expenditure in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in low density lipoprotein (LDL) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in total cholesterol (TC) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Changes in weight in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in HDL between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
  • Compared the changes in body fat between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))

Study Sites (1)

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