Health Effects of Reducing Sedentary Behavior
- Conditions
- General Population
- Interventions
- Behavioral: Reducing sedentary behaviorBehavioral: ControlBehavioral: Reducing stress
- Registration Number
- NCT03609255
- Lead Sponsor
- Texas Tech University
- Brief Summary
A recent review indicated that sedentary behavior has been associated with increased morbidity and mortality but the intervention studies frequently focus only on changing sedentary behavior (reducing sedentary time) without measuring health-associated outcomes. Elevated cortisol (related to stress) has been linked with health risks. Improved physical fitness has been linked with improved cortisol responses to psychosocial stressors. In addition, increased physical activity induced favorable effects upon low density lipoprotein, high density lipoprotein, and total cholesterol. Previous study also indicated that increasing daily steps have positive effect on blood glucose in people with impaired glucose tolerance. Ultimately, the investigators think that sedentary intervention and stress management may have benefits on these health indicators. As such the investigators will examine whether sedentary intervention or stress management can have positive effect on human health by measuring salivary cortisol, blood lipid profile, fasting blood glucose, blood pressure, resting energy expenditure, and body composition.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 21
- Age: 18-65 years.
- Unable/unwilling to provide informed consent.
- Having mobility impairment.
- Current severe untreated depression (i.e., score in the severe depression range on the Hospital Anxiety and Depression Scale; HADS).
- Women who are pregnant or nursing.
- Currently smoking (within last 12 months).
- Currently use medications that affect salivary cortisol level (i.e. prednisone, dexamethasone).
- Have been diagnosed Addison's disease.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Sedentary behavior group (SB) Reducing sedentary behavior - Control group (C) Control - Stress management group (SR) Reducing stress -
- Primary Outcome Measures
Name Time Method Compare the changes of stress levels between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compare the changes of stress levels as measured via salivary cortisol between SB and SR.
Stress improvement in stress management group (SR) Baseline (pre-intervention) and 4 weeks (post-intervention) Improvement in stress as measured via salivary cortisol in SR.
Stress improvement in sedentary behavior group (SB) Baseline (pre-intervention) and 4 weeks (post-intervention) Improvement in stress as measured via salivary cortisol in SB.
Daily steps Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in daily steps measured via pedometer.
- Secondary Outcome Measures
Name Time Method Changes in body fat in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in body fat as measured via BODPOD in SB.
Changes in total cholesterol (TC) in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in TC as measured via finger stick in SB.
Changes in blood pressure in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in blood pressure as measured via Omron Digital BP Monitor HEM-907XL in SB.
Compared the changes in weight between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in weight between SB and SR.
Changes in high density lipoprotein (HDL) in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in HDL as measured via finger stick in SB.
Changes in low density lipoprotein (LDL) in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in LDL as measured via finger stick in SB.
Changes in blood pressure in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in blood pressure as measured via Omron Digital BP Monitor HEM-907XL in SR.
Compared the changes in TG between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in TG between SB and SR.
Changes in fasting blood glucose in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in fasting blood glucose as measured via finger stick in SB.
Compared the changes in TC between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in TC between SB and SR.
Changes in triglyceride (TG) in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in TG as measured via finger stick in SB.
Changes in weight in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in weight as measured via BODPOD in SB.
Changes in high density lipoprotein (HDL) in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in HDL as measured via finger stick in SR.
Compared the changes in LDL between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in LDL between SB and SR.
Compared the changes in fasting blood glucose between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in fasting blood glucose between SB and SR.
Compared the changes in blood pressure between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in blood pressure between SB and SR.
Change in resting energy expenditure in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Change in resting energy expenditure as measured by metabolic cart in SR.
Changes in triglyceride (TG) in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in TG as measured via finger stick in SR.
Changes in fasting blood glucose in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in fasting blood glucose as measured via finger stick in SR.
Changes in body fat in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in body fat as measured via BODPOD in SR.
Change in resting energy expenditure in SB Baseline (pre-intervention) and 4 weeks (post-intervention) Change in resting energy expenditure as measured by metabolic cart in SB.
Changes in low density lipoprotein (LDL) in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in LDL as measured via finger stick in SR.
Changes in total cholesterol (TC) in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in TC as measured via finger stick in SR.
Changes in weight in SR Baseline (pre-intervention) and 4 weeks (post-intervention) Changes in weight as measured via BODPOD in SR.
Compared the changes in HDL between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in HDL between SB and SR.
Compared the changes in body fat between SB and SR Baseline (pre-intervention) and 4 weeks (post-intervention) Compared the changes in body fat between SB and SR.
Trial Locations
- Locations (1)
Texas Tech University - Department of Nutritional Sciences
🇺🇸Lubbock, Texas, United States