The Effectiveness of Low Level Laser Therapy on Particular Joint Points and Acupuncture Points on Knee Joints in Grade III Knee Osteoarthritis

Not Applicable

Recruiting

• Conditions: Knee Osteoarthritis

• Registration Number: NCT05403931
• Lead Sponsor: Universiti Teknologi Malaysia

Brief Summary

LLLT is in use to treat different musculoskeletal condition. Osteoarthritis is one of the conditions needing LLLT for therapeutic effects. LLLT has been used in different previous studies using different points on joint and also on acupuncture points. This study is going to compare the effectiveness of LLLT on both points. Omega xp device is going to be used in this study.

Detailed Description

LLLT is a non-invasive modality to treat variety of musculoskeletal conditions. Photobiomodulation has been studies for last two decades in different perspectives and on different musculoskeletal condition. Studies suggest profound results due to effect of LLLT at the cellular level. Osteoarthritis is one of the most common debilitating musculoskeletal condition affecting people worldwide. Statistics indicate an increase in this debilitating condition in future. Knee OA is more common amongst other OA of the body. LLLT has been used in previous studies to see the impact on pain and functional performance in knee OA. LLLT has been used on different points on knee joint and also applied on acupuncture points of the knee joints. Different outcomes were used to assess LLLT effectiveness including pain, ROM and even different biomarkers. This study is going to use LLLT on different particular joint points of knee and also acupuncture points of the knee joint and compare the outcomes. This study will present evidence for the clinicians to use LLLT on either the particular joint points or acupuncture points for better clinical outcomes.

Study Timeline

• Study Start: 2022-04-30
• Study First Submitted: 2022-05-06
• Study First Submitted QC: 2022-05-29
• Study First Posted: 2022-06-03
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-16
• Last Update Posted: 2023-05-17
• Primary Completion: 2023-07-30
• Study Completion: 2023-09-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Pain in the knee joint ( minimum 30/100 on VAS )

  • Kellgren-Lawrence Grade III knee OA

  • ACR criteria for knee OA with radiological findings including ;

    • age 35 and above
    • joint crepitus
    • less than 30 minutes of morning stiffness

Exclusion Criteria

• Knee OA grade other than III.

  • Any contraindication of LLLT including;

    • pregnancy
    • carcinoma involving knee area

  • Steroids and NSAIDS use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Timed Up and Go test ( TUG )	16th week	Timed Up and Go test assesses the balance and is widely used in the clinical outcomes assessment. It's measured in seconds. Lesser the time means good balance and longer the time means poor balance.
Visual Analog Scale ( VAS )	16th week	Visual Analog Scale is a widely used tool to assess pain in knee OA. The score ranges from 0-100. 0 means no pain and 100 means the worst pain.
Western Ontario and McMaster University Osteoarthritis Index ( WOMAC )	16th week	Western Ontario and McMaster University Osteoarthritis Index is a standard questionnaire used in knee OA to assess the outcome of an intervention. It's 24 items scale which covers pain, stiffness and function. The score ranges from 0-96. 0 means the best health or best performance and 96 is the worst health status or performance.

Trial Locations

Locations (1)

Central Park Teaching Hospital; 🇵🇰 Lahore, Punjab, Pakistan