Effect of dexmed vs midazolam infusion on inflammatory biomarkers in sepsis patients
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/05/052530
- Lead Sponsor
- DIKSHA CHOUDHARY
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
In sepsis (patient fulfilling SIRS criteria of sepsis).
Patient on mechanical ventilation.
Patient having sequential organ failure assessment (SOFA) score of 2 or more.
1.Patients with history of severe cardiac or pulmonary disease, poorly controlled hypertension.
2.Known hypersensitivity to study drugs or using any drug that modifies pain perception.
3.Refusal to participate
4.Have unpaced second or third degree heart block
5.Have uncontrolled hypotension
6.Have acute cerebrovascular conditions
7.Concurrently using other alpha-2 agonists, eg, clonidine
8.Cautions for the following patients who are: -
a.Are at risk of exaggerated cardiovascular response, e.g., hypovolaemia
b.Have spinal cord injury
c.Have severe left ventricular systolic dysfunction
d.Are pregnant
e.Breast-feeding
f.Have seizures disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method