Screening of thyroid function after therapeutically applied iodine contrast medium in infants and toddlers with congenital heart defects
Recruiting
- Conditions
- E03.2Hypothyroidism due to medicaments and other exogenous substances
- Registration Number
- DRKS00009843
- Lead Sponsor
- niversitäts Herzzentrum Freiburg Bad KrozingenAbteilung für angeborene Herzfehler und pädiatrische Kardiologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Newborns and infants till the age of 6 months with congenital heart defect and regular heart catheterization
Normal thyroid function before application of iodinated contrast medium
Application of > 4 ml/kg body weight iodinated contract medium
Exclusion Criteria
Thyroid dysfunction before heart catheterization
Application of < 4 ml/kg body weight of iodinated contrast medium
Others diseases which may influence thyroid function as gastrointestinal diseases or autoimmune diseases
Medications which may influence thyroid function as amiodarone, dopamine, glucocorticoids
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome is a thyroid dysfunction as hypothyroidism<br><br>A potential thyroid dysfunction is investigated by measurement of thyroid hormones before catheterization as baseline, on days 3 - 5, 10 - 14 und 24 - 28 after catheterization.
- Secondary Outcome Measures
Name Time Method