Floseal Posterior Epistaxis Pilot Study (PEPIS)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 主要终点
- Effectiveness of Floseal for the Treatment of Posterior Epistaxis.
研究概览
简要总结
Effectiveness of Floseal for the treatment of posterior epistaxis.
详细描述
Floseal, a hemostatic agent, is an effective treatment for anterior epistaxis as well as numerous other acute bleeding conditions throughout the body. The investigators hypothesize that Floseal is an effective treatment for posterior epistaxis. If so, then this will also lead to significant cost savings in comparison to any other method of treatment of posterior epistaxis. The investigators have planned a prospective, nonblinded, nonrandomised study with a total of 40 subjects with posterior epistaxis to be included in this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age greater than 18 years of age
- •posterior epistaxis
排除标准
- •patients with anterior epistaxis
- •known sensitivity to any of the materials of Floseal or the topical medications administered as part of the evaluation and treatment of epistaxis (lidocaine, xylometazoline hydrochloride)
- •pregnant or breast feeding woman
研究组 & 干预措施
Floseal
Received 1 syringe of Floseal for treatment of posterior epistaxis.
干预措施: Floseal (Drug)
结局指标
主要结局
Effectiveness of Floseal for the Treatment of Posterior Epistaxis.
时间窗: Immediate effect with 1 hour observation and follow-up at 5 and 30 days following treatment.
Successful treatment using the gelatin-thrombin matrix protocol (Floseal) was any case of posterior epistaxis that stopped following the immediate application of either one or two syringes of Floseal® and the epistaxis did not resume within fourteen days of the treatment date.
次要结局
- Cost Savings of Floseal Treatment in Comparison to Posterior Packing, Surgical, and Embolisation Treatments for Posterior Epistaxis.(30 days)