Different Intra-abdominal Pressures and Optic Nerve Size

Completed

• Conditions: Intraabdominal Hypertension; Optic Nerve Congestion; Major Surgery
• Interventions: Procedure: Intraabdominal pressure and optic nerve diameters

• Registration Number: NCT04556877
• Lead Sponsor: Trakya University

Brief Summary

In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Detailed Description

In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. This situation creates ischemia in the abdominal organs in the patient, decreases venous return as a result of inferior vena cava compression and leads to a decrease in cardiac output. In addition, intracranial pressure frequently increases as a result of the venous circulation being affected. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Study Timeline

• Study Start: 2018-06-15
• Primary Completion: 2020-06-15
• Study Completion: 2020-06-15
• Status Verified: 2020-09
• Study First Submitted: 2020-09-07
• Study First Submitted QC: 2020-09-18
• Last Update Submitted: 2020-09-18
• Study First Posted: 2020-09-21
• Last Update Posted: 2020-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

Having had major abdominal surgery

Exclusion Criteria

1. pregnant patients
2. Patients whose bladder catheter cannot be inserted
3. Patients with diagnosed or suspected brain death

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Intraabdominal pressure under 12 mmHg	Intraabdominal pressure and optic nerve diameters	Patients with intraabdominal pressure under 12 mmHg
Intraabdominal pressure between 12-20 mmHg	Intraabdominal pressure and optic nerve diameters	Patients with intraabdominal pressure between 12-20 mmHg
Intraabdominal pressure over 20 mmHg	Intraabdominal pressure and optic nerve diameters	Patients with intraabdominal pressure over 20 mmHg

Primary Outcome Measures

Name	Time	Method
optic nerve diameter	at 24.hour	measuring optic nerve diameter

Trial Locations

Locations (1)

Trakya University; 🇹🇷 Edirne, Turkey