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Effect of oral Magnesium in diabetic neuropathy

Phase 3
Recruiting
Conditions
Peripheral polyneuropathy in type 2 diabetes.
Type 2 diabetes mellitus with diabetic polyneuropathy
E11.42
Registration Number
IRCT20230522058258N1
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

Men and women between the ages of 20 and 85
Having type 2 diabetes (whose type 2 diabetes has already been proven by tests of FBS > 126 and HbA1c > 6.5 and they are being treated with oral antidiabetic drugs or insulin)
Having the symptoms of distal peripheral polyneuropathy: feeling pain and excessive sensitivity or reduced sensation or feeling of burning, tingling and murmur in the hands or feet of the patient

Exclusion Criteria

Suffering from other neuropathies other than diabetic neuropathy
Neuromuscular diseases (such as myasthenia gravis)
Magnesium level above 2.1
History of magnesium consumption in the last 3 months
A history of persistent diarrhea and vomiting
History of diuretic use with a dose of more than 40 mg
History of thyroid diseases or levothyroxine use
History of heart block or use of calcium channel blockers
Having chronic kidney disease (GFR<60)
Taking antidepressants, anticonvulsants, or analgesics
Pregnancy and breastfeeding
History of any malignancy
History of amputation or active diabetic foot ulcer

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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