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Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy

Phase 3
Completed
Conditions
Hip Disease
Interventions
Registration Number
NCT03432650
Lead Sponsor
Hospital for Special Surgery, New York
Brief Summary

Hip arthroscopy is performed frequently and the postoperative course often involves moderate to severe pain. There remains no definitive perioperative pain regimen that has been proven to be effective and safe for this ambulatory procedure. Some institutions perform peripheral nerve blocks either preoperatively or postoperatively as a rescue block. All of these PNBs lead to quadriceps weakness which may impede earlier mobilization and physical therapy. While some case reports exist, there have not been any studies evaluating the QLB for hip arthroscopy patients. As previously mentioned, the technique is easy to perform, well-tolerated by patients, and avoids side effects such as hypotension, urinary retention, or the quadriceps weakness associated with lumbar plexus blockade.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
96
Inclusion Criteria
  • Patients scheduled for hip arthroscopy
  • Ability to follow study protocol
  • English Speaking
Exclusion Criteria
  • Hepatic or renal insufficiency
  • Younger than 18 years old and older than 80
  • Allergy or intolerance to one of the study medications
  • Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
  • Chronic opioid use (daily opioids use for longer than 3 months)
  • Patients contraindicated to undergo a spinal anesthetic
  • Non English Speakers

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
QLB Block + Standard of CareUltrasoundPatients will receive either a spinal (4cc Mepivacaine) or combined spinal epidural anesthetic (dose up 50 5 cc 2% lidocaine) with IV sedation. Intraoperative anti-emetics will consist of IV ondansetron and IV dexamethasone. Intra-operative analgesics will be IV fentanyl, IV acetaminophen, IV ketorolac, and IV ketamine. No Block will be given. Patients will receive a single shot anterior QLB (30cc 0.5% Bupivacaine with 2mg preservative free dexamethasone).
QLB Block + Standard of CareBupivacaine + dexamethasonePatients will receive either a spinal (4cc Mepivacaine) or combined spinal epidural anesthetic (dose up 50 5 cc 2% lidocaine) with IV sedation. Intraoperative anti-emetics will consist of IV ondansetron and IV dexamethasone. Intra-operative analgesics will be IV fentanyl, IV acetaminophen, IV ketorolac, and IV ketamine. No Block will be given. Patients will receive a single shot anterior QLB (30cc 0.5% Bupivacaine with 2mg preservative free dexamethasone).
Primary Outcome Measures
NameTimeMethod
Numerical Pain Rating System (NRS) Pain Scores24 hours after Post Anesthesia Care Unite (PACU) arrival

Pain scores at rest and with movement will be through 24 hours after surgery. Score scale is from 0-10. 0 means no pain, 10 means worst pain. A lower score is a better outcome.

Secondary Outcome Measures
NameTimeMethod
Number of Patients With Presence of IAFE (Intraabdominal Fluid Extravasation) Following SurgeryImmediately post-op in OR
Incidence of HypotensionUp to Post Op Day 1
Opioid UseAfter Surgery to Post Operative Day 1

Amount of opioids taken after surgery

Antiemetic UseUp to Post Op Day 1
Patient Satisfaction With Post Op Pain ControlUp to Post Op Day 1

Scale of 0-10; 0 being extremely dissatisfied and 10 being extremely satisfied

Change in Quadriceps Motor Strength on Surgical SideUp to Post Op Day 1

Change in Quadriceps Motor Strength from Pre-Op Baseline Quadriceps Strength

Number of Participants With Hospital AdmissionUp to Post Op Day 1
Urinary RetentionUp to Post Op Day 1

Incidence of Urinary Retention in recovery

Number of Patients With Nausea/VomitingUp to Post Op Day 1
Patient Score on Quality of Recovery-40 (QoR40) Inventory.Up to Post Op Day 1

Validated QoR40 survey score. Survey questions are added up to provide a final score. Higher score is reflective of a better outcome. Minimum score is 40, maximum score is 200.

Trial Locations

Locations (1)

Hospital of Special Surgery

🇺🇸

New York, New York, United States

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