Randomized double blind controlled trial to assess the safety and efficacy of three investigational herbal preparations (nut meg based preparation, sudarshana churna, coriandum based preparation) for the treatment of patients with COVID-19
- Conditions
- COVID 19
- Registration Number
- SLCTR/2021/008
- Lead Sponsor
- niversity of Peradeniya
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- Not specified
1. Patients who understands and agrees to comply with planned study procedures.
3. Patients who agree to the collection of nasopharyngeal swabs and venous blood per protocol.
4. Male >18 years or non-pregnant female adult >18 years of age at the time of enrolement.
5. Has a laboratory confirmed SARS-CoV-2 infection as determined by positive PCR done within 72 hrs, with a quantitative PCR cycle threshold (qPCR Ct value ) which is less than 25 and a positive Rapid antigen testing (RAT) performed at the point of admission.
1. Known patients with chronic liver disease and kidney disease
2. Alanine amino transferase (ALT) or Aspartate amino transferase (AST) or Serum creatinine> 2 times the upper limit of normal.
3. Pregnancy or breast feeding.
4. Anticipated transfer to another hospital which is not a study site within 72 hours.
5. Allergy to any study medication
6. Treatment with another investigational drug or other intervention
7. Patients who are on warfarin, glucocorticoids and other immuno-suppressive medications or anti-cancer medications
8. Patients with known substance abuse
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method