Evaluation of walking in patients with Parkinson's disease who underwent surgery for brain stimulation before and after physical therapy program with exercises and treadmill training with or without body weight support.

Not Applicable

• Conditions: Parkison's disease, Neurological Gait Disorders; C10.228.140.079.862.500; C10.597.404

• Registration Number: RBR-6fftwy
• Lead Sponsor: Faculdade de Medicina da Universidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-09-16
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Other
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Indication of the implant deep brain stimulation; Over 18 years of age, clinical diagnosis of idiopathic Parkinson's disease according to international criteria, absence of adequate response to treatment with medication or with complications related to prolonged use of L-dopa; Expected to be anesthesia or local anesthesia or general do not incur greater risk than expected in the general population; Ability to understand and sign the consent form; Blood tests, coagulation and normal metabolic; Absence of anatomic abnormalities that preclude access to the implant the electrodes (cranial tumors, intra-cranial and brain cysts), absence of infection or other medical conditions pre-existing non-controlled (diabetes, hypertension, symptomatic pulmonary or cardiac diseases) no use of antiplatelet agents, not being performing concurrent treatment with other experimental drugs; Absence of pregnancy and breastfeeding; conditions psychological, familial, sociological or geographical impossible medical monitoring post-operative Fitness for Motor Training Program, Maintenance of good clinical conditions previously described; Maintenance of all clinics and drug restrictions described; Installation of deep brain stimulation (DBS) for two months at least; DBS working properly at the time of inclusion; Accept and sign the consent form to participate in the training program.

Exclusion Criteria

Inability to consent to participate in the study: With uncontrolled infection or other medical conditions pre-existing non-controlled (eg decompensated diabetes, hypertension, pneumonia or symptomatic heart disease), history of primary or secondary myocardial ischemia, congestive heart failure, cardiac arrhythmia, or bundle branch block refractory to treatment, concomitant treatment with other experimental drugs, pregnant or lactating; Conditions psychological, familial, sociological or geographical conditions that preclude medical monitoring post-operative history of orthopedic surgery of lower limbs.

Study & Design

• Study Type: Intervention
• Study Design: Not specified