The effect of short term intensive cognitive training using repetitive transcranial magnetic stimulation for mild cognitive impairment

Phase 3

Recruiting

• Conditions: Mild cognitive impairment; forgetfullness, MCI; D060825

• Registration Number: JPRN-jRCTs032220329
• Lead Sponsor: Takakura Tomokazu

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-09-12
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1.Be aware of forgetfulness.
2.Housework and activities of daily living are generally normal.
3.Age more than or equal to 60 years and less tha 80 years.
4.Those who can go to the hospital according to the test protocol.
5.Written informed consent to participate in this study.

Exclusion Criteria

1.Under treatment for epilepsy/depression/mania/ schizophrenia.
2.Who have a cardiac pacemaker, implantable defibrillator, metal near the stimulation site (cochlear implant, magnetic clip, deep brain stimulation / vagus nerve stimulation), or implantable drug solution pump.
3. Severe heart disease:unstable angina,short-term myocardial infarction from onset, decompensated congestive heart failure, acute pulmonary heart, uncontrolled arrhythmia, severe aortic stenosis, active Myocarditis, endocarditis, etc.
4. Uncontrolled hypertension
5. Acute systemic illness or fever
6. Complications of recent pulmonary embolism, acute cor pulmonale, and severe pulmonary hypertension
7. Complication of severe hepatic / renal dysfunction
8. Severe orthopedic complications
9. Severe cognitive impairment (MMSE-J less tha or equal to 20/30), complications of severe mental illness
10. Other metabolic disorders (such as acute thyroiditis)
11. When using drugs that lower the threshold of spasm attacks (tricyclic antidepressants, maprotiline, theophylline, methylphenidate, ketamine, clozapine, zotepine) and abuse of alcohol, caffeine, stimulants, etc.
12. Lactating women
13. Other patients who are judged by the research-responsible (sharing) doctor to be inappropriate as research subjects.

Study & Design

• Study Type: Interventional
• Study Design: Not specified