Protein metabolism in chronic kidney disease

Not Applicable

Completed

• Conditions: Chronic kidney disease; Urological and Genital Diseases; Chronic kidney disease, unspecified

• Registration Number: ISRCTN64383094
• Lead Sponsor: Fresenius Kabi Deutschland GmbH (Germany)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02-21
• Last Update Posted: 24 July 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Aged 18-79, both males and females
2. Non-diabetic CKD (Stages 4-5, estimated glomerular filtration rate [eGFR] 12-25 ml/min)
3. Compliance to treatment

Exclusion Criteria

1. Evidence of congestive heart failure
2. Incapable of following study requirements to control diet
3. A recent myocardial infarction
4. Pregnancy
5. Unstable renal function
6. Recent (<3 months) infection history
7. Clinical evidence of gastrointestinal or liver diseases
8. Alcoholism
9. Drug abuse
10. Final diagnosis of malignancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Protein metabolism measured at baseline and at the end of each six-week experimental period

Secondary Outcome Measures

Name	Time	Method
Serum/muscle myostatin measured at baseline and at the end of each six-week experimental period