The effect of a low protein diet compared with a high protein diet on food reward

Completed

Conditions: obesitas
obesity
overweight

Registration Number: NL-OMON37647

Lead Sponsor: Wageningen Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 24

Inclusion Criteria

Pag. 8 protocol:
• Age: 18-35 years
• BMI: 18.5 - 25.0 kg/m2
• Healthy (as judged by the participant)

Exclusion Criteria

Pag. 8 protocol:
• Restraint eating (men: score > 2.25; women: score > 2.80)
• Lack of appetite
• Having difficulties with swallowing/eating
• Usage of an energy restricted diet during the last two months
• Weight loss or weight gain of 5 kg or more during the last two months
• Stomach or bowel diseases
• Kidney disorders
• Diabetes, thyroid disease, other endocrine disorders
• Having a history of neurological disorders
• Having taste or smell disorders
• Usage of daily medication other than birth control pills
• Pregnant or lactating
• Smoking more than one cigarette a day
• Being a vegetarian
• Being allergic/intolerant for products under study
• Working at the division of human nutrition (WUR)
• Having participated in *ProTime*, or current participation in other research from the division of
Human Nutrition (WUR).
• Having a contra-indication to MRI scanning (see page 9 of protocol)

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Our main outcome measurement is the change in brain reward response to sight<br /><br>and smell of high and low protein food stimuli after the 16-day low protein and<br /><br>high protein diets.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• To assess the effect of a 16-day low protein diet on different aspects of<br /><br>food reward: the explicit liking, the explicit wanting, the implicit wanting<br /><br>and a forced food choice of high and low protein food using the computerized<br /><br>Leeds Food Preference Questionnaire (LFPQ) compared with a high protein diet.<br /><br>• To assess the effect of a 16-day low protein diet on protein and energy<br /><br>intake compared with a high protein diet.</p><br>