Intraoperative Wound Ventilation with Carbon Dioxide.
Completed
- Conditions
- Aortic arch surgery.
- Registration Number
- NL-OMON24534
- Lead Sponsor
- St.-Antonius Ziekenhuis, Nieuwegeindepartement of Cardio-thoracic Surgery
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients accepted for elective aortic arch surgery (with or without concomitant surgery on the ascending aorta or other heart related surgery).
Exclusion Criteria
1. Emergency operation;
2. Severely calcified or sclerotic aorta or cerebropetal vessels;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ess microembolism assessed by Trans-Cranial Doppler (TCD) monitoring of the left and right middle cerebral artery.
- Secondary Outcome Measures
Name Time Method eurological outcome assessed by clinical neurological testing and neurocognitive outcome assessed by comprehensive neuropsychometric studies (intelligence, problem-solving, concentration, learning, memory, error-free performance, mood abnormalities, and dexterity are components of the general neuropsychological system, and all of these have been included in the term cognitive functions). These testings are performed the day before surgery, the day before hospital discharge and 3 months postoperatively.<br /><br>Morphologic alterations of the brain are searched for by comparing preoperative and postoperative diffusion-weighted MR-imaging scans of the brain.