The effect of supplementing fish oil and aspirin on blood levels of factors involved in the resolution of inflammation in healthy men and wome

Not Applicable

Completed

• Conditions: ow level inflammation; Low level inflammation; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12610000740099
• Lead Sponsor: Professor Trevor Mori

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-09-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Men aged 20-70 years, and post-menopausal women aged less than 70 years will be recruited from the general population by newspaper advertisements. Volunteers will be included if they do not meet any of the criteria for the metabolic syndrome as defined by the National Cholesterol Education Program Adult Treatment Panel III (NCEP: ATPIII).

Exclusion Criteria

Smokers, history of cardiovascular or peripheral vascular disease, diabetes, renal disease, liver disease or taking anti-hypertensive agents, lipid lowering drugs, hormone replacement therapy (women only), > 2 standard alcoholic drinks for women and >3 standard alcoholic drinks for men per day, aspirin or non-steroidal anti-inflammatory drugs, omega-3 fatty acids or >2 fish meals per week.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma anti-inflammatory resolvins and protectins[Blood samples will be taken at days 0, 5 and 7]

Secondary Outcome Measures

Name	Time	Method
Fasting plasma fatty acids[Blood samples will be taken at days 0, 5 and 7]