Assessment of the impact of nephrectomy on cardiovascular risk in living kidney donors: longitudinal follow-up. Focus on endothelial dysfunction, inflammation and oxidative stress.
Not Applicable
Recruiting
- Conditions
- Cardiovascular diseaseRenal and Urogenital - Other renal and urogenital disorders
- Registration Number
- ACTRN12610000141044
- Lead Sponsor
- niversity of Queensland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Patients who fulfill the live donation selection process and successfully complete donor nephrectomy
Exclusion Criteria
Patients from areas in Queensland where follow up vascular studies can not be carried out for logistic reasons.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Carotid intima media thickness (ultrasound of vascular structure)[This study is planned for 5 years with baseline and subsequent review every 12 months.]
- Secondary Outcome Measures
Name Time Method Brachial artery reactivity (ultrasound of vascular function)[Baseline and every 12 months for 5 years]