Does exercise training result in weight loss?

Not Applicable

Completed

• Conditions: Overweight and obesity in women; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN31641049
• Lead Sponsor: niversity of Ottawa

Brief Summary

2019 Results article in https://pubmed.ncbi.nlm.nih.gov/31507431/ (added 27/02/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2012-12-11
• Study Start: 2019-01-04
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 21

Inclusion Criteria

1. Aged 20-45 years
2. Female
3. Stable weight for the last 2 months
4. Body mass index (BMI) >30 kg/m²
5. Sedentary (no more than 2 hours of structured physical activity per week)
6. Menstrual periods every month

Exclusion Criteria

1. Pregnancy
2. Smokers
3. Drug users
4. Consuming more than 2 units of alcohol per day
5. Claustrophobic
6. Use of nutritional supplements
7. Not using oral contraceptives or hormones
8. Diabetic (type 1 or type 2)
9. Thyroid disorders
10. Renal disease
11. Liver disease
12. Cancer
13. Inflammatory disease
14. Asthma
15. Respiratory problems
16. Cardiovascular disease
17. Peripheral vascular disease
18. Stroke
19. Orthopaedic limitations
20. Using any of the following:
20.1. Systemic corticosteroids (e.g. prednisone)
20.2. Anti-obesity agents (e.g. Xenical®, Meridia®)
20.3. Natural supplemented for weight loss or weight control (e.g. Megace)
20.4. Antipsychotics
20.5. Mood stabilisers or antidepressants that have a significant impact on weight (e.g. Zyprexa®, Remeron®)
20.6. Diuretics (e.g. Lasix®, furosemide)
21. Treatment with thyroid hormones (stable dose for at least 3 months before the start of the study)
22. Use of thiazide diuretics (hydrochlotozide) for less than 3 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> The following were assessed during 3 data collection phases - a 7 day baseline phase (1 month prior to the exercise intervention), a 14 day phase at the beginning of the intervention, and a 7 day phase at the end of the intervention (after 3 months):<br> 1. Energy intake, assessed using lunch boxes and a food journal (according to McNeil et al., 2012)<br> 2. Energy expenditure, assessed using doubly labelled water (according to Schoeller and van Santen, 1982).<br> 3. Body composition, assessed using dual X-ray absorptiometry<br>

Secondary Outcome Measures

Name	Time	Method
<br> The following were assessed during 3 data collection phases - a 7 day baseline phase (1 month prior to the exercise intervention), a 14 day phase at the beginning of the intervention, and a 7 day phase at the end of the intervention (after 3 months):<br> 1. Appetite, assessed using a visual analogue scale (VAS)<br> 2. Eating behaviour traits, assessed using the Three-Factor Eating Questionnaire (TFEQ)<br> 3. Food rewards, assessed using the Leeds Food Preference Questionnaire (LFPQ)<br> 4. Time spent performing activities, assessed using an accelerometer<br>