Bright Light Therapy for Non-motor Symptoms in Parkinson's Disease
Not Applicable
- Conditions
- Parkinson's Disease
- Interventions
- Device: Light Therapy Device
- Registration Number
- NCT02909192
- Lead Sponsor
- Massachusetts General Hospital
- Brief Summary
Disruption of sleep and alertness is one of the most disabling non-motor symptoms of Parkinson's disease (PD). Mechanisms leading to impaired sleep and alertness in PD are not well understood, and treatment options remain limited. The proposed research will examine markers of the circadian system, sleepiness and sleep quality in PD patients. Further, the project will examine effects of bright light exposure on circadin function, sleep and alertness in PD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 65
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Dim-Red light therapy Light Therapy Device Participants will be treated twice daily with dim-red light therapy. Bright light therapy Light Therapy Device Participants will be treated twice daily with bright light therapy.
- Primary Outcome Measures
Name Time Method Parkinson's Disease Sleep Scale (PDSS-2) score to measure sleep quality 8 weeks
- Secondary Outcome Measures
Name Time Method Epworth Sleepiness Scale (ESS) score to measure daytime sleepiness 8 weeks Plasma melatonin levels collected through blood samples to measure melatonin amplitude and circadian regulation 8 weeks Non-Motor Symptoms Assessment Scale for Parkinson's Disease (NMSS) score to measure the severity and frequency of non-motor symptoms 8 weeks
Trial Locations
- Locations (1)
Massachusetts General Hospital
🇺🇸Boston, Massachusetts, United States